Methodological and clinical aspects of ictal MEG

Epilepsy is relatively frequent disease affecting about 0.7% of general population. About 25% of epilepsy patients are resistant to pharmacological treatment. In this situation epilepsy surgery may by an option. The most efficient form of epilepsy surgery is epileptogenic zone (EZ) resection. Ictal onset zone (IOZ) is an essential part of EZ and therefore the evaluation of location and configuration of IOZ is one of the most important goals of pre-surgery workup. The main non-invasive method which provides the information about IOZ is video-EEG, another well known non-invasive technique is ictal SPECT.