Children conceived by IVF: specifics of mental development

The study focuses on the problem of mental development of children conceived by in vitro fertilization (IVF) and presents the results of a comparative research of cognitive development of 135 children conceived spontaneously and 135 children conceived by IVF, aged from 11 to 37 months. Data were collected at the Center for Family Planning and Reproduction, Moscow. We used diagnostics of infants’ neuropsychological development (E.L. Frukht), psycho-pedagogical study of mental development of early-aged children (E.A. Strebeleva) and medical history data. We found peculiarities in cognitive development of early-aged children conceived by IVF compared with those conceived spontaneously. Children born after 4-9 IVF cycles have demonstrated cognitive development lags significantly more often than those conceived naturally or after 1-3 IVF cycles. Among children conceived spontaneously share of children with normal cognitive development did not differ on the first, second and third years of life; in a group of children conceived after 1-3 IVF cycles, number of children with normal cognitive development increased from first to third year.

1. Barashnev Ju.I. Osobennosti zdorov'ja detej, rozhdennyh zhenshhinami s pomoshh'ju vspomogatel'nyh reproduktivnyh tehnologij [Specific of health of children born by women using assisted reproductive technologies]. Rossijskij vestnik perinatologii i pediatrii [Russian Bulletin of Perinatology and Pediatrics], 2004. № 5. P. 12–17.
2. Evsjukova I.I., Masljanjuk N.A. Sostojanie novorozhdennyh i ih dal'nejshee razvitie pri mnogoplodnoj beremennosti posle JeKO [State of newborns and their further development in multiple pregnancies after IVF]. Problemy reprodukcii [Russian Journal of Human Reproduction], 2005. № 2. P. 52–54.
3. Kuznecova V.S. i dr. Osobennosti adaptacii v rannem neonatal'nom periode novorozhdennyh detej, rozhdennyh u zhenshhin s besplodiem v anamneze posle ciklov jekstrakorporal'nogo oplodotvorenija [Features of adaptation in the early neonatal period of newborn infants born by women with an infertility in anamnesis after in vitro fertilization cycles]. Zhurn. teoreticheskoj i prakticheskoj mediciny [Journal of Theoretical and Practical Medicine]. 2004. Vol. 2. № 1. P. 59–62.
4. Lancburg M.E. Rol' psihologicheskoj podgotovki i podderzhki v realizacii roditel'skih funkcij [The role of psychological training and support in realization of parenting]. Psihologicheskaja nauka i obrazovanie [Psychological Science and Education], 2011. № 1. P.15–26.
5. Lancburg M.E. Psihologicheskaja sluzhba podderzhki beremennyh zhenshhin i molodyh roditelej [Psychological support service for pregnant women and young parents]. Psihologicheskaja nauka i obrazovanie [Psychological Science and Education], 2004. № 3. P. 88–97.
6. Lancburg M.E., Solov'eva E.V. Osobennosti poznavatel'nogo razvitija detej rannego vozrasta, zachatyh posredstvom jekstrakorporal'nogo oplodotvorenija [Features of cognitive development of toddlers conceived by in vitro fertilization]. Materialy II Nacional'nogo kongressa «Diskussionnye voprosy sovremennogo akusherstva». Sankt-Peterburg. 2013. Zhurn. akusherstva i zhenskih boleznej [Journal of Obstetrics and Women's Diseases]. 2013. Vol. LXII. Specvypusk. P. 40.
7. Plaksina A.N., Kovtun O.P., Blohina S.I. Ocenka pokazatelej kachestva zhizni detej, rozhdennyh pri pomoshhi vspomogatel'nyh reproduktivnyh tehnologij [Evaluation of quality of life of children born using assisted reproductive technologies]. Elektronnyi nauchnyi zhurnal «Sistemnaja integracija v zdravoohranenii» [Electronic scientific journal «System Integration in health care»], 2011. № 1. Available at: http://www.sys-int.ru/ru/journals/2011/1-11/ocenka-pokazateley-kachestva-zhizni-detey-rozhdennyh-pri-pomoshchi-vspomogatelnyh (Accessed 15.01.2014).
8. Rishhuk S.V., Mirskij V.E. Sostojanie zdorov'ja detej i osobennosti techenija beremennosti posle primenenija vspomogatel'nyh reproduktivnyh tehnologij [Children's health and the features of pregnancy after assisted reproductive technologies] TERRA MEDICA NOVA, 2010. № 1. Available at: http://www.terramedica.spb.ru/all/public/pdf/terra/1-60-2010-f115.pdf (Accessed 15.01.2014).
9. Strebeleva E.A. Metodicheskie rekomendacii k psihologo-pedagogicheskomu izucheniju detej (2-3 let): Rannjaja diagnostika umstvennogo razvitija [Guidelines for psycho-pedagogical study of children (2-3 years): Early diagnosis of mental development]. Al'manah instituta korrekcionnoj pedagogiki RAO [Almanac of Institute of Correctional Pedagogy RAO], 2001. №. 4. P. 3-26.
10. Pantiukhina G.V., Pechora K.L., Frukht E.L. Metody diagnostiki nervno-psikhicheskogo razvitiia detei rannego vozrasta [Methods of diagnosis of nervous and mental development of early-aged children]. Moscow: VUNMC, 1996. 76 p.
11. Colpin H., Soenen S. Parenting and psychosocial development of IVF children: a follow-up study. Human Reproduction. 2002. № 17(4). Р. 1116–1123.
12. Golombok S., Cook R., Bish A., Murray C. Families created by the new reproductive technologies: quality of parenting and social and emotional development of the children. Child Development. 1995. № 64(2). Р. 285–298.
13. Golombok S., Brewaeys A., Cook R., et al. The European study of assisted reproduction families: Family functioning and child development . Human Reproduction. 1996. № 11. Р. 2324–2331.
14. Klemetti R., et al. Health of children born as a result of in vitro fertilization. Pediatrics. 2006. Vol.118. № 5. Р. 1819–1827.
15. Squires J., Kaplan P. Developmental outcomes of children born after assisted reproductive technologies. Infants and Young Children. 2007. Vol. 20. № 1. P. 2–10.